Xenotransplantation - Whole Blood and Components
Also known as: xenografts
Essential information
- Definition/s
Xenotransplantation: any procedure that involves the transplantation, implantation, or infusion into a human recipient of either (a) live cells, tissues, or organs from a non-human animal source, or (b) human body fluids, cells, tissues, or organs that have had ex vivo contact with live, non-human animal cells, tissues, or organs. Xenotransplantation products include live cells, tissues and organs.
Biological products, drugs, or medical devices sourced from non-living cells, tissues or organs from non-human animals including, but not limited to, porcine insulin, porcine heart valves and acellular porcine collagen matrix are not considered xenotransplantation products.
Inoculation injuries from non human sources are not considered to be xenotransplants.
- Includes
Heterografts, non-human organ perfusion, xenografts and xenotransplant recipients.
- Obligatory
Scenarios
Xenotransplant recipient
- Includes
- Excludes
- Obligatory
Must not donate if:
Material from a living non-human animal source has been directly or indirectly in contact with the donor's blood supply. This does not include animal bites.
- Additional information
Exposure to non-human animal material, particularly when the person exposed is immunosuppressed, may result in unusual infections, that would not normally affect humans, being passed on to recipients of donated material. Inoculation injury, involving non-human animals, does not fall into the category of xenotransplantation.
Current for former sexual partner of xenotransplant recipient
- Includes
- Excludes
- Obligatory
Must not donate.
- Additional information
Sexual partners of individuals who have received a xenotransplant may potentially be at risk of acquiring an unusual infection that may be passed on by donated material. Because the duration of any risk is not known, deferral must be permanent.
- Reason for change:
- Reference to specific products has been removed from the Definitions section.
- Version details:
WB-DSG Edition 203 Release 67 (31 January 2023)