Conn's syndrome - Whole Blood and Components

Essential information

Excludes

Secondary hyperaldosteronism

Obligatory

Must not donate.

Discretionary

If donor has undergone surgery for a benign adrenal tumour (adenoma), the donor is fully recovered, has been discharged from follow up and is not on medication for Conn’s syndrome, accept.

Supporting information

See if relevant

• Blood pressure, high
• Diuertics

Additional information

Conn’s syndrome (primary hyperaldosteronism) is caused by overproduction of aldosterone in the adrenal cortex. Aldosterone is a hormone that regulates potassium and sodium levels as well as fluid balance in the body thereby maintaining blood volume and blood pressure, helping the body to control stress and maintain a steady metabolic state and normal electrolyte balance.

Secondary hyperaldosteronism is caused by increased adrenal production by medical conditions outside the adrenal gland which stimulates the renin- angiotensin- aldosterone mechanism.