Xenotransplantation - Tissue - Deceased Donors

Also known as: xenografts

Essential information

Definition/s

Any procedure that involves the transplantation, implantation, or infusion into a human recipient of either (a) live cells, tissues, or organs from a non-human animal source, or (b) human body fluids, cells, tissues, or organs that have had ex vivo contact with live, non-human animal cells, tissues, or organs. Xenotransplantation products include live cells, tissues and organs.

Biological products, drugs, or medical devices sourced from nonliving cells, tissues or organs from non-human animals, including but not limited to porcine insulin, porcine heart valves, and collagen matrices derived from acellular porcine, bovine or any other xenogeneic source (e.g. PelviSoft®, Bio-Oss®, Bio-Gide® and Surgibone®) are not considered xenotransplantation products.

Includes

Xenografts, heterografts, non-human organ perfusion.

Obligatory

Scenarios

Recipient

Includes

Excludes

Obligatory

Must not donate if:

Material from a living non-human animal source has been directly or indirectly in contact with the donor's blood supply. This does not include animal bites.

Current or former sexual partners of xenotransplant recipients

Includes

Excludes

Obligatory

Must not donate.

Additional information

Exposure to non-human animal material, particularly when the person exposed is immunosuppressed, may result in infections that would not normally affect humans being passed on.

Reason for change:

Further guidance re Recipient definition

Version details:

TD-DSG Edition 203 Release 25 (13 July 2016)