Prion-associated diseases - Tissue - Deceased Donors

Essential information

Includes

Sporadic, Familial and Variant Creutzfeldt-Jakob Disease (CJD), Gerstmann-Strãussler-Scheinker Disease, Fatal Familial Insomnia.

Obligatory

Must not donate if:

  1. Diagnosed with any form of CJD, or other human prion disease.

  2. Identified at increased risk of developing a prion associated disorder.
    This includes:
    1. Individuals at familial risk of prion-associated diseases (have had two or more blood relatives develop a prion-associated disease or have been informed following genetic counselling they are at risk).
    2. Individuals who have potentially been put at increased risk from surgery, transfusion or transplant of tissues or organs.
    3. Individuals who have been told that they may be at increased risk because a recipient of blood or tissues that they have donated has developed a prion related disorder.
    4. Recipients of dura mater grafts.
    5. Recipients of corneal, scleral or other ocular tissue grafts.
    6. Recipients of human pituitary derived extracts.
    7. Since January 1st 1980:
      Recipients of any allogeneic human tissue.
Discretionary

If the donor has had two or more blood relatives develop a prion-associated disease and, following genetic counselling, they have been informed that they are not at risk, accept.

This requires confirmation by a Designated Medical Officer.

Supporting information

See if relevant
Additional information

A Position Statement on Creutzfeldt-Jakob Disease is available.

Reason for change:
The entry has been modified to comply with advice from the MSBTO committee of the DH. Appropriate links have been added.
Version details:

TD-DSG Edition 203 Release 23 (18 January 2018)