Hepatitis of unknown origin - Tissue - Deceased Donors
Scenarios
Affected individual
- Obligatory
Must not donate if:
Less than 24 months from recovery.
- Discretionary
- If more than 12 months, but less than 24 months from recovery, obtain history and blood samples and refer to a Designated Medical Officer.
- If more than 24 months from recovery, accept.
- If more than 12 months and less than 24 months from recovery:
- If negative for all markers of hepatitis B, accept.
- If HB core antibody is positive and HBsAg is negative, HBV-DNA is negative and anti-HBs has been documented at more than 100 IU/L at some time, accept.
- If more than 12 months, but less than 24 months from recovery, obtain history and blood samples and refer to a Designated Medical Officer.
Sexual partner of an affected individual
- Obligatory
Must not donate if:
Less than 12 months from recovery of partner.
Person sharing a home with an affected individual
- Obligatory
Must not donate if:
Less than 12 months from recovery of the last affected person in the home.
- See if relevant
- Sexual partner of an affected individual above
- Additional information
Most hepatitis of unknown origin will have been due to hepatitis A or hepatitis E (or non-viral causes). Additional testing for those who give a history of hepatitis between 12 and 24 months before donation will exclude the rare case of HBV which may have delayed clearance of infection and therefore will still present a risk through donation.
- Reason for change:
- Clarification regarding hepatitis B markers has been added to the additional information.
- Version details:
TD-DSG Edition 203 Release 17 (31 March 2013)