Gout - Bone Marrow and Peripheral Blood Stem Cell
Essential information
- Obligatory
Must not donate.
- Discretionary
- For bone marrow donors:
Accept. - For PBSC donors:
Discuss with DCSO.
See Additional Information.
- For bone marrow donors:
Supporting information
- Additional information
Gout is an acute arthritis caused by build-up of uric acid crystals in the joint space. There have been reports of severe exacerbation of gout following administration of G-CSF.
In the interests of donor protection, caution should be exercised before considering donors with gout for PBSC donation. In these circumstances, donors should be counselled about the possibility of exacerbation of their condition and consent to this before proceeding to receive G-CSF.
Affected individuals should be excluded from PBSC donation unless permitted by DCSO based on individual risk assessment.
- Reason for change:
- Exclude affected individuals from donation of PBSC unless permitted by DCSO.
- Version details:
BM-DSG Edition 203 Release 54 (29 January 2024)